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KMID : 0370219960400030343
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Yakhak Hoeji
1996 Volume.40 No. 3 p.343 ~ p.346
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Effect of a New Fluoroquinolone LB20304a on Microflora of Caecum in Mice
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안미정/Ahn MJ
백경숙/김무용/김인철/곽진환/Paek KS/Kim MY/Kim IC/Kwak JH
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Abstract
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The influence of LB20304a, a new fluoroquinolone antibiotic agent, on microflora of caecum in mice was compared with those of ciprofloxacin and piperacillin after administration of drugs for 5 days. Selective medium (CCFMA) was used for the isolation of Clostridium difficile from the specimens of mouse caecum. The emergence of C. difficile in mouse caecum induced by LB20304a was lower than that by ciprofloxacin or piperacillin at day 1 and day 7 after completing administration of drugs.
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